Professor of Biomedical Informatics
University of Utah School of Medicine

30 North 1900 East
Salt Lake City, UT 84132
contact address


Dr. Guilherme Del Fiol earned his MD from the University of Sao Paulo, Brazil; his MS in Computer Science from the Catholic University of Parana, Brazil; and his PhD in Biomedical Informatics from the University of Utah. He is currently Professor and Vice-Chair for Research in the University of Utah’s Department of Biomedical Informatics. Prior to the University of Utah, Dr. Del Fiol held positions in Clinical Knowledge Management at Intermountain Healthcare and as faculty at the Duke Community and Family Medicine Department. Since 2008, he has served as an elected co-chair of the Clinical Decision Support Work Group at Health Level International (HL7). He is also an elected Fellow of the American College of Medical Informatics (ACMI) and a member of the Comprehensive Cancer Center at Huntsman Cancer Institute.

Dr. Del Fiol's research interests are in the design, development, evaluation, and dissemination of standards-based clinical decision support interventions. He has been focusing particularly on interventions to improve cancer prevention and reduce health disparities. He is the lead author of the HL7 Infobutton Standard and the project lead for OpenInfobutton, an open source suite of infobutton tools and Web services, which is in production use at several healthcare organizations throughout the United States, including Intermountain Healthcare, Duke University, and the Veterans Health Administration (VHA). His research has been funded by various sources including the National Library of Medicine (NLM), National Cancer Institute (NCI), AHRQ, CMS, CDC, and PCORI.

Selected Bibliography:

Shi J, Morgan KL, Bradshaw RL, Jung SH, Kohlmann W, Kaphingst KA, Kawamoto K, Fiol GD.
Identifying Patients Who Meet Criteria for Genetic Testing of Hereditary Cancers Based on Structured and Unstructured Family Health History Data in the Electronic Health Record: Natural Language Processing Approach.
JMIR Med Inform. 2022;10(8):e37842. PubMed abstract / Full Text

Wiley K, Findley L, Goldrich M, Rakhra-Burris TK, Stevens A, Williams P, Bult CJ, Chisholm R, Deverka P, Ginsburg GS, Green ED, Jarvik G, Mensah GA, Ramos E, Relling MV, Roden DM, Rowley R, Alterovitz G, Aronson S, Bastarache L, Cimino JJ, Crowgey EL, Del Fiol G, Freimuth RR, Hoffman MA, Jeff J, Johnson K, Kawamoto K, Madhavan S, Mendonca EA, Ohno-Machado L, Pratap S, Taylor CO, Ritchie MD, Walton N, Weng C, Zayas-Cabán T, Manolio TA, Williams MS.
A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources.
J Am Med Inform Assoc. 2022;29(8):1342-1349. PubMed abstract / Full Text

Reese T, Wright A, Liu S, Boyce R, Romero A, Del Fiol G, Kawamoto K, Malone D.
Improving the specificity of drug-drug interaction alerts: Can it be done?.
Am J Health Syst Pharm. 2022;79(13):1086-1095. PubMed abstract / Full Text

Kukhareva PV, Caverly TJ, Li H, Katki HA, Cheung LC, Reese TJ, Del Fiol G, Hess R, Wetter DW, Zhang Y, Taft TY, Flynn MC, Kawamoto K.
Inaccuracies in electronic health records smoking data and a potential approach to address resulting underestimation in determining lung cancer screening eligibility.
J Am Med Inform Assoc. 2022;29(5):779-788. PubMed abstract / Full Text

Bradshaw RL, Kawamoto K, Kaphingst KA, Kohlmann WK, Hess R, Flynn MC, Nanjo CJ, Warner PB, Shi J, Morgan K, Kimball K, Ranade-Kharkar P, Ginsburg O, Goodman M, Chambers R, Mann D, Narus SP, Gonzalez J, Loomis S, Chan P, Monahan R, Borsato EP, Shields DE, Martin DK, Kessler CM, Del Fiol G.
GARDE: a standards-based clinical decision support platform for identifying population health management cohorts.
J Am Med Inform Assoc. 2022;29(5):928-936. PubMed abstract / Full Text