Causes of SUDEP in children might be different than those in adults. Childhood deaths in children with epilepsy may be more often due to their underlying disorder. SUDEP may occur more frequently in children with developmental delay/intellectual disability, children with difficult to control seizures,and children with seizures that began early in the child's life. [Weber: 2005] [Camfield: 2005] In addition, children with SUDEP were more likely to be sleeping in a prone position and to have generalized tonic-clonic epilepsy. [McGregor: 2006] Polypharmacy and low serum antiepileptic medication levels are found in autopsies of adults with SUDEP, but not necessarily in autopsies of children. Some investigators believe that good seizure control may help prevent SUDEP. [Tomson: 2005]
Some investigators have found that children with epilepsy who are typically developing have no increase in risk of death compared to the general population, [Camfield: 2005] however other studies suggest that SUDEP is found in children with idiopathic and symptomatic epilepsy. [Donner: 2001]
|Author:||Lynne M Kerr, MD, PhD - 6/2011|
|Content Last Updated:||6/2011|
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Sudden unexpected death in people with epilepsy: a pediatric perspective.
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Sudden unexplained death in children with epilepsy.
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