Rachelle Nuss, MD

Professor, University of Colorado School of Medicine
Associate Director, Colorado Sickle Cell Treatment and Research Center

The Children’s Hospital
Colorado Sickle Cell Treatment and Research Center
13121 E. 17th Ave, C-222

Aurora, CO 80045


Dr. Nuss has been with the University of Colorado since 1988. She directs the pediatric program of the Colorado Sickle Cell Treatment and Research Center at The Children’s Hospital in Denver and conducts outreach clinics in Colorado Springs.

Dr. Nuss is a site principal investigator for multi-center clinical trials for children with sickle cell disease; she has led investigator-initiated translational and early phase clinical studies, and collaborates with basic science investigators.

Selected Bibliography:

Nuss R.
Red cell transfusions for patients with sickle cell disease: do we have more to learn?.
Pediatr Blood Cancer. 2010;54(4):499-500. PubMed abstract

McKinney CM, Siringo F, Olson JL, Capocelli KE, Ambruso DR, Nuss R.
Red cell exchange transfusion halts progressive proliferative sickle cell retinopathy in a teenaged patient with hemoglobin SC disease.
Pediatr Blood Cancer. 2015;62(4):721-3. PubMed abstract

Lasalle-Williams M, Nuss R, Le T, Cole L, Hassell K, Murphy JR, Ambruso DR.
Extended red blood cell antigen matching for transfusions in sickle cell disease: a review of a 14-year experience from a single center (CME).
Transfusion. 2011;51(8):1732-9. PubMed abstract

Goodman J, Hassell K, Irwin D, Witkowski EH, Nuss R.
The splenic syndrome in individuals with sickle cell trait.
High Alt Med Biol. 2014;15(4):468-71. PubMed abstract / Full Text

Gladwin MT, Kato GJ, Weiner D, Onyekwere OC, Dampier C, Hsu L, Hagar RW, Howard T, Nuss R, Okam MM, Tremonti CK, Berman B, Villella A, Krishnamurti L, Lanzkron S, Castro O, Gordeuk VR, Coles WA, Peters-Lawrence M, Nichols J, Hall MK, Hildesheim M, Blackwelder WC, Baldassarre J, Casella JF.
Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial.
JAMA. 2011;305(9):893-902. PubMed abstract / Full Text