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Asthma - Treatment & Management

Overview

Management recommendations are from the 2007 National Heart, Lung, and Blood Institute (NHLBI) Guidelines [National: 2007]. They differ according to age group, 0-4 years of age, 5-11 years, and youths > 12 years of age. Although inhaled corticosteroids (ICS) remain the preferred long-term control in all groups, several more medication options, such as long-acting beta2 agonists and omalizumab, may be used as an alternative in children 12 and older and adults.

Goals of Treatment:

Reduce impairment by:
  • Preventing chronic and troublesome symptoms (e.g., cough, breathlessness);
  • Decreasing symptoms enough that only infrequent use (2 days a week or less) of inhaled SABA for quick relief is required;
  • Maintaining (near) normal pulmonary function;
  • Maintaining normal activity levels, including exercise and school/work attendance;
  • Meeting families' and patients' expectations of and satisfaction with, asthma care.
Reduce risk by:
  • Preventing recurrent exacerbations of asthma and minimizing the need for ED visits or hospitalizations;
  • Preventing loss of lung function (maximizing lung growth in children);
  • Providing optimal pharmacotherapy with minimal or no adverse effects.
If the child with asthma is not responding well to treatment, consider an alternative diagnosis for the child's symptoms and referral to an asthma specialist for clarification.

Primary Care Roles

The 2007 National Heart, Lung, and Blood Institute (NHLBI) Guidelines [National: 2007] recommend multifaceted asthma treatment:
  1. Treating the patient for their current level of severity (for new patients) and control (for patients already on asthma medications), as well as for their risk for exacerbation.
  2. Arranging follow-up depending on their current level of severity and control. Frequency will depend on many factors including severity of asthma and risk of exacerbations, familiarity of the family with asthma and medications used to treat it, etc. After an initial diagnosis or an exacerbation, consider a return visit in two weeks to assess response to treatment and ability of the family to accurately assess and adequately respond to symptoms.
  3. Teaching the patient and family self-monitoring of their asthma. See the Patient self-assessment record (2007 NHLBI Guidelines) (PDF Document 54 KB) for an easy to fill out form for symptom monitoring.
  4. Developing and sharing an asthma action plan.
  5. Education, and perhaps referral, regarding environmental control. Patients who are sensitive to allergens and pollutants or irritants should be advised to decrease their exposure to these substances, including cockroach, dust-mite, rodent, and house pet allergens. Other topics include exposure to aspirin or nonsteroidal anti-inflammatory drugs, use of indoor air-cleaning devices, and decreased use of humidifiers and/or evaporative coolers. See Environmental modifications for asthma (2007 NHLBI Guidelines) (PDF Document 69 KB) . Although allergy and asthma share many of the same mechanisms and the treatment of allergy is important in the treatment of many children with asthma, clear relationships between persistent asthma symptoms and particular allergens should exist before allergy testing and treatment.
  6. Ongoing education regarding the disease and treatment. See Educational goals for asthma (2007 NHLBI Guidelines) (PDF Document 97 KB) for more information.
  7. Consider inactivated influenza vaccination for all children with asthma.
  8. Evaluate and treat comorbid conditions such as gastro-esophageal reflux disease (GERD), obesity, sinusitis, stress and depression, and obstructive sleep apnea.
  9. Local asthma resources should be discussed with families, e.g., asthma camps and parent organizations. (see Services)
  10. Educate the family that secondhand smoking can exacerbate asthma. Family members can be referred to Keeping Your Natural Beauty: A Smoker's Guide to Quitting, Quit Smoking (CDC), and I Quit! What to do when you're sick of smoking (PDF Document) for stopping smoking resources.

Pearls And Alerts

Bronchospasm that occurs with exercise in a child that does not otherwise have symptoms of asthma may respond to the use of inhaled beta2-agonists before exercise. See the Special Situations section of the guidelines, page 363 ([National: 2007]) and Exercise induced bronchospasm.

Practice Guidelines

National Asthma Education and Prevention Program Expert Panel.
Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma - Summary Report 2007.
National Institutes of Health: National Heart, Lung, and Blood Institute; (2007) http://www.nhlbi.nih.gov/guidelines/asthma/asthsumm.htm. Accessed on 3/31/08.

Systems

Respiratory

Initiating Treatment: At the initial visit in children who have not yet received treatment for asthma, the child's asthma should be classified by severity (based on the most severe symptoms) and by risk for exacerbation (see Initial Assessment page or the Tools below). Once severity and risk are classified, these parameters guide the level of treatment at which to begin. Treatment of a child with an established diagnosis of asthma is based on the level of control (See below). The following Tools are simplified from the 2007 NHLBI Guidelines [National: 2007]. For the original, more detailed tables from the Guidelines, see the end of this section.


Ongoing treatment: The link to the Asthma Control Test, a validated test for asthma symptoms in children with an established diagnosis of asthma as well as quick checklists for determining asthma control for children with ongoing asthma adapted from the tables in the Guidelines [National: 2007] are provided immediately following. The child is classified by their current asthma control (based on the most severe symptoms) and risk in order to guide any needed adjustments in management or therapy using the asthma treatment stepwise tables. Full tables from the Guidelines are provided at the end of this section.

In a child with asthma who has been in excellent control with little risk for three months or more, a step-down from one treatment level to another may be considered.
In a child with poorly controlled asthma who has had frequent exacerbations and is using an inhaled SABA more than twice a week, a step up to the next treatment level should be considered. Before stepping up, adherence to medication, knowledge of inhaler technique, and control of comorbid and environmental cofactors should be reviewed. These and more in depth recommendations are also available for various classifications of asthma control on the Checklist for asthma control above and the Asthma treatment tables from the Guidelines, below.

Original tables for assessing asthma severity (for the new patient) and control (for ongoing care) and stepwise treatment from the Guidelines ([National: 2007]) are available as pdf files below. Additional information regarding dosages and medications is available through the tables below. These medication tables are also from [National: 2007].

Subspecialist Collaborations and Other Resources

A referral for specialty consultation and/or management should be considered if control has been erratic.

Pediatric Pulmonology (see Services below for relevant providers)

An asthma specialist might be helpful if symptoms are atypical or if additional testing, such as a challenge, are needed for diagnosis. Also consider referral for specialty consultation and/or management when: two or more bursts of oral steroids are needed within 6 months, an exacerbation requires hospitalization, care is at the step 4 level or higher, immuno-therapy is being considered, or additional testing is needed.

Pediatric Allergy (see Services below for relevant providers)

Consider referral for subcutaneous allergen immunotherapy if there is an obvious relationship between persistent asthma symptoms and sensitivity to a particular allergen, and for asthma management in refractory cases as described above.

Resources

Practice Guidelines

National Asthma Education and Prevention Program Expert Panel.
Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma - Summary Report 2007.
National Institutes of Health: National Heart, Lung, and Blood Institute; (2007) http://www.nhlbi.nih.gov/guidelines/asthma/asthsumm.htm. Accessed on 3/31/08.

Patient Education

Asthma (MedlinePlus)
Asthma information and tutorials, in English and Spanish, from the National Library of Medicine.

Asthma and Allergy Foundation provider education website
Information for providers from the Asthma and Allergy Foundation regarding their 2 hour asthma educational program, as well as patient education materials in English and Spanish.

Breathing Easier information - Spanish (Intermountain Health Care, UT) (PDF Document 1.6 MB)
Spanish version of Intermountain Health Care's asthma patient information. Para respirar mas facil, con asma.

Breathing Easier, Information (Intermountain Health Care, Utah) (PDF Document 2.9 MB)
Information in English and Spanish for asthma patients and their families, including diagnosis, management, and how to use nebulizers and inhalers.

NHLBI National Asthma Education and Prevention Program
This website offers links to information about asthma for providers, families, and schools.

Tools

Asthma Control Test
An easy to use, online asthma control test for evaluating control based on recent symptoms. Site is sponsored by a pharmaceutical company but appears to be free of advertising.

Asthma action plan, Spanish (PDF Document)
This child asthma action plan in Spanish is from the EPR Guidelines, 2007, and is adapted by them from the California asthma resources.

Asthma action plan, adult, English, Spanish, and Chinese (PDF Document)
These asthma action plans are from the Asthma EPR Guidelines, 2007, and are adapted from California's asthma resources.

Asthma action plan, child, English (PDF Document)
This asthma action plan is from the Asthma EPR Guidelines, 2007, and is adapted from California's asthma resources.

Asthma control/risk grid, 0-4 yrs (PDF Document 79 KB)
A symptom grid for classification of asthma control and risk to guide treatment, adapted from the 2007 NHLBI Guidelines for Asthma Diagnosis and Management

Asthma control/risk grid, 12 yrs & up (PDF Document 77 KB)
A symptom grid for classification of asthma control and risk to guide treatment, adapted from the 2007 NHLBI Guidelines for Asthma Diagnosis and Management

Asthma control/risk grid, 5-11 yrs (PDF Document 79 KB)
A symptom grid for classification of asthma control and risk to guide treatment, adapted from the 2007 NHLBI Guidelines for Asthma Diagnosis and Management

Asthma severity/risk grid, 0-4 yrs (PDF Document 74 KB)
A symptom grid for asthma classification of new patients to guide treatment, adapted from the 2007 NHLBI Asthma Guidelines.

Asthma severity/risk grid, 12 yrs & up (PDF Document 76 KB)
A symptom grid for asthma classification of new patients to guide treatment, adapted from the 2007 NHLBI Asthma Guidelines.

Asthma severity/risk grid, 5-11 yrs (PDF Document 82 KB)
A symptom grid for asthma classification of new patients to guide treatment, adapted from the 2007 NHLBI Asthma Guidelines.

Initiating treatment table - children (2007 Guidelines, NHBLI) (PDF Document 575 KB)
Asthma severity classification table from the 2007 NHLBI Guidelines for the Diagnosis and Management of Asthma for new patients.

Initiating treatment table - youths and adults (2007 Guidelines, NHLBI) (PDF Document 617 KB)
Asthma severity classification table from the 2007 NHLBI Guidelines for the Diagnosis and Management of Asthma for new patients.

Ongoing management table - children (2007 Guidelines, NHLBI) (PDF Document 707 KB)
Tables to assess asthma control in ongoing patient assessments to allow classification for stepwise treatment. From the 2007 NHLBI Guidelines for Asthma Diagnosis and Management.

Ongoing management table - youths and adults (2007 Guidelines, NHLBI) (PDF Document 996 KB)
Tables to assess asthma control in ongoing patient assessments to allow classification for stepwise treatment. From the 2007 NHLBI Guidelines for Asthma Diagnosis and Management.

Patient self-assessment record (2007 NHLBI Guidelines) (PDF Document 54 KB)
A sample record for patients to track asthma symptoms and medication use from the 2007 NHLBI Guidelines.

Stepwise treatment table - children (2007 Guidelines, NHLBI) (PDF Document 212 KB)
Stepwise treatment table for children from the 2007 NHLBI Guidelines summary.

Stepwise treatment table - youths and adults (2007 Guidelines, NHLBI) (PDF Document 887 KB)
Stepwise treatment tables for youths and adults from the 2007 NHLBI Guidelines for the Diagnosis and Management of Asthma.

Services

Pediatric Allergy

See all Pediatric Allergy services providers (7) in our database.

Pediatric Pulmonology

Pediatric Asthma Program, more info...
100 N Mario Capecchi Dr
Salt Lake City, UT 84103
Phone: 801-662-1765
http://intermountainhealthcare.org/xp/public/primary/docsclinics/clinics/asthma.xml

See all Pediatric Pulmonology services providers (5) in our database.

For other services related to this condition, browse our Services categories or search our database.

Authors

Lead Author: Lynne M Kerr MD, PhD, 3/2008
Reviewing Author: Derek Uchida MD, 3/2008
Content Last Updated: 3/2008

Page Bibliography

National Asthma Education and Prevention Program Expert Panel.
Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma - Summary Report 2007.
National Institutes of Health: National Heart, Lung, and Blood Institute; (2007) http://www.nhlbi.nih.gov/guidelines/asthma/asthsumm.htm. Accessed on 3/31/08.